For example, eIF4E overexpression is frequently found in patients with colorectal cancer (CRC) or breast cancer (BC) [37, 38]; eIF5A2 overexpression is obviously associated with the advanced stage of ovarian cancer [39]; eIF3D increases cell cycle progression and motility in prostate cancer (PCa) [40]. The gene discussed is EIF3D; the disease is posterior cortical atrophy.