The replicated results also included 30 new protein associations, not previously reported to be associated with MetS, including neural cell adhesion molecule L1-like protein (CHL1), complement factor I (CFI), GDNF family receptor alpha-1 (GFRA1), kallikrein-8 (KLK8), brevican core protein (BCAN), dickkopf-like protein 1 (DKKL1), netrin receptor (UNC5D), NTR domain-containing protein 2 (WFIKKN2), and endoplasmic reticulum protein 29 (ERP29). The gene discussed is UNC5D; the disease is metabolic syndrome.