Of the 5 in the INT, 1 stopped after 2 injections due to covid-19 and the risk of getting infected by contact to hospital staff, 1 stopped after 2 injections due to a non-related event (myocardial infarction pre-existing coronary stenosis), 1 stopped after 2 injections because of increased liver parameters (classified as related), 1 stopped after 3 injections due to increased perspiration and facial hirsutism (related) and 1 missed 1 injection due to slightly increased PSA value (related). This evidence concerns the gene KLK3 and coronary stenosis.