A recent proteomic profiling study pointed to DC-SIGN as a mediator of genetic risk in COVID-19 [36] and finally DC/L-SIGN expression is induced by proinflammatory cytokines such as IL-4, IL-6, IL-10 and IL-13, known to be overexpressed in severe SARS and COVID-19 cases [37,38]. This evidence concerns the gene IL6 and COVID-19.