Despite this difference, rs7041 was associated with a 4.5-fold reduction in VDBP, i.e. 271.9, 149.4, and 49.9 ug/mL for 0, 1, and 2 copies of rs7041-A, respectively, consistent with prior results in a European-derived population [20], but with approximately two fold lower levels of VDBP by genotype in this African American population with T2D. Here, GC is linked to type 2 diabetes mellitus.