34, 35, 36, 37 Additionally, AIM2 inflammasome activation and IL‐1β secretion are involved in the process of CD137L‐mediated monocyte to DC differentiation, which triggers a stronger T cell response against cancer‐associated viruses90. In contrast, AIM2 inflammasome activation and high levels of IL‐1α production in plasmacytoid dendritic cells (pDCs) can facilitate lung cancer cell proliferation.91 This evidence concerns the gene IL1A and lung carcinoma.