IFNB1 and neoplasm: Besides, elevated levels of AIM2 in the tumor stroma can also suppress tumor cells in TRAIL‐sensitive triple‐negative breast cancers.130, 151 TRAIL‐expressing human mesenchymal stem/stromal cells (hMSCs) promote apoptosis and inhibit metastasis of breast cancer cells (MDA cells) after TNF‐α treatment by secreting IFN‐β.