TfRC expression is correlated with poorer outcomes in several cancers, the overexpression of TfRC provided more irons to meet the metabolic needs of the cancer cells while downregulation of TfRC has inhibited the growth of tumor (Jiang et al., 2010; Pham et al., 2014; Voth et al., 2015; Shen et al., 2018). The gene discussed is TFRC; the disease is neoplasm.