In a study of multi-line nivolumab treatment in those patients who have KRAS-mutant NSCLC (20), regardless of KRAS status, there were similar remission rates: overall response rate ([ORR] 20% vs. 17%; P = 0.39), DCR (47% vs. 41%; P = 0.23), median PFS (4 months vs. 3 months; P = 0.5), and OS (11.2 months vs. 10 months; P = 0.8). This evidence concerns the gene KRAS and non-small cell lung carcinoma.