TFF3 and metastatic malignant neoplasm in the lymph nodes: Furthermore, the most upregulated genes specific for intestinal gastric cancer subset resulted OLFM4, involved in early gastric carcinogenesis and associated with prognostic significance in advanced stages (115), CDH17 and TFF3, specific markers of intestinal metaplasia gastric cancer patients (116), TRIM29, identified as oncogene in gastric cancer marker of lymph node metastasis (117, 118), and SYT8, a promising target for the detection, prediction, and treatment of peritoneal metastasis of gastric cancer (119).