SERPINE1 and gastric adenocarcinoma: Among inflammatory pathways, we found also an overexpression of several genes identified as diagnostic or prognostic markers of gastric cancer including E2F1, that induces upregulation of lncRNA HCG18 thus stimulating proliferation and migration of gastric cancer (96), TIMP1, a key gene in the development of gastric cancer recognized as a potential prognostic marker when co-expressed with MMP-7 (97, 98), S100A9, a diagnostic and prognostic biomarker in gastric cancer (99, 100), and SERPINE1, highly expressed and significantly related to a poor prognosis of gastric adenocarcinoma (90).