MALAT1 and hepatocellular carcinoma: To validate that MALAT1 physically bound to miRNAs and served as a miRNA sponge in breast cancer, miR-3064-5p was chosen for further experiments, because miR-3064-5p has been reported to inhibit cell proliferation and invasion in ovarian cancer and to suppress angiogenesis in hepatocellular carcinoma (34, 35).