CD4 and neoplasm: In order to further explore significant individual variation seen in the overall DNA and RNA data, we plotted the RNA expression data of each individual patient’s tumor infiltrating CD4+ T cell samples against blood (Figure 3C), and observed that expression of most of the lineage determining genes as well as the major cytokines showed variability among patients, except for FOXP3, which was upregulated in most patients (3 of 5 patients).