Interestingly, we observed significantly lower values of the pro-apoptotic gene BAX and significantly higher values of the anti-apoptotic gene BCL2 in 3D bioprinted CLL primary cells as compared to 2D cultured ones, analyzed after 7 days, independently of their clinical/biological features (Figures 8A, B) (n = 16). The gene discussed is BCL2; the disease is B-cell chronic lymphocytic leukemia.