Moreover, this study reported that lupus monocytes aberrantly express MIC, without distinguishing MICA from MICB, and that sera from SLE patients induce MIC expression by monocytes from healthy individuals in a partly IFN-γ-dependent manner (suggesting that other circulating factors are involved, e.g. nucleosomes). The gene discussed is MICB; the disease is systemic lupus erythematosus.