No difference between healthy male volunteers and PCa patients was found in the SARS-CoV-2 cross-reacting CD4+ T cell populations (Figure 7C).These data showed that the HCoV-229E peptide pool can partially rescue the patients’ compromised responsiveness to the SARS-CoV-2 peptide pool due to the HCoV-229E peptide pool-mediated enhanced enrichment of the patients’ cells with CD4+ T cells, which cross-react with the SARS-CoV-2 peptide pool. Here, CD4 is linked to posterior cortical atrophy.