We evaluated the expression of these miRNAs in the kidneys of our LPS mice, and found that only the expression of miR-18a-3p was negatively correlated with that of MEG3. Previous studies have reported that miR-18a-3p is down-regulated in the cruciate ligament of patients with osteoarthritis (Li et al., 2017). The gene discussed is MEG3; the disease is osteoarthritis.