CD8A and neoplasm: A higher fraction of tumor-bearing mice survived after they were adoptively transferred with CFSE-negative P14 CD8+ Teff cells pre-cultured with activated CD28WTCD8+ T cells (71.7% survival, group I), compared to those that were adoptively transferred with P14 CD8+ Teff cells pre-cultured with activated CD28KOCD8+ T cells (51.4% survival, group II) (Fig. 6d).