PDCD5 and pulmonary fibrosis: To further verify induction of PDCD5 expression in TGF-β-driven lung fibrosis, we next evaluated changes in PDCD5 expression in a transgenic mouse model with inducible overexpression of TGF-β1 (Ccsp-TGFβ1-TG mice), which induces lung fibrosis after administration of doxycycline (Dox).