One intergenic SNP between SORCS1 and LINC01435 [rs1890078; P = 6.64 × 10−7, OR = 0.43 (95% CI: 0.30–0.61)] showed higher MAF allele, C in control samples as a protective effect associated with reduced risk of AD (Fig. 3). This evidence concerns the gene SORCS1 and Alzheimer disease.