Furthermore, we performed RNA-seq and gene set enrichment analysis (GSEA) of six human NB cell lines (MYCN amplified SK-N-BE2, BE(2)-C, NLF, SK-N-DZ, and MYCN non-amplified SHEP, SK-N-AS), and found that MYCN expression is closely associated with levels of ferroptosis-related genes as summarized by Liang et al.18 (Fig. 1B and Supplementary Table 1). This evidence concerns the gene MYCN and neuroblastoma.