In theory, the detection of TERT signals in a histologically confirmed FTC could therefore imply an underlying TERT gene aberrancy, which in turn is strongly associated with worse patient outcome.9 Moreover, studies using preoperative fine-needle aspiration biopsy material could also be valuable, as the expression of TERT could imply a clinically more burdensome tumour in need of more extensive interventions. This evidence concerns the gene TERT and thyroid cancer, nonmedullary, 2.