NPM1 and acute myeloid leukemia: Among the patients with CK-AML, WT1 gene had the highest mutational incidence (13%) followed by CEBPA, FLT3/ITD, and IDH1 genes (6.0% each), and none was observed in NPM1, KIT, CCND1, IDH2, ASXL2, DHX15, and DNMT3A genes (Table 1).