Specifically, participant #553 has a germline mutation (BRCA1: c.5328delC) along with a family history of vulvar cancer, #750 has a known pathogenic mutation (BRCA1: c.5212G > A) with a family history of breast and ovarian cancer, #2754 is a carrier of a pathogenic mutation (BRCA1: c.5251C > T) with a family history of breast cancer, prostate cancer and basal cell carcinoma (BCC) of the skin, and finally PABC patient #2740 carries a germline mutation (BRCA1 g.169527_180579del11052) and has a history of endometrial and lung cancer. This evidence concerns the gene BRCA1 and lung carcinoma.