Ticagrelor has also proven to be effective and safe in patients with type 2 diabetes.[32] Thomas et al[33] conducted a subgroup analysis of type 2 diabetes, and the results suggested that the platelet inhibitory effect before and after the maintenance dose of ticagrelor 60 mg group has nothing to do with type 2 diabetes and whether to use insulin. This evidence concerns the gene INS and type 2 diabetes mellitus.