However, the results of subgroup analyses by ethnicity showed a significant association of VDR FokI mutation with disc degeneration risk in Caucasians (Recessive model, OR with 95%CI 1.301, [1.041, 1.626], Additive model, OR with 95%CI 1.119, [1.006, 1.245]). Here, VDR is linked to intervertebral disk degenerative disorder.