Because we are interested in the response against fungal infection, we repeated the experiment using a model of peritonitis where 1 × 107Aspergillus fumigatus germinating conidia (spores) expressing cell-surface β-Glucan were heat killed and injected into the peritoneal cavity of WT, Il1a−/−, Il1b−/−, and Il1a−/−/ Il1b−/− double-knockout (DKO) mice. The gene discussed is IL1A; the disease is peritonitis.