CD4 and tuberculosis: Nonetheless, there are situations that require more urgent ART starting, such as pregnant women, due to HIV vertical transmission impact; people with severe comorbidities, such as active tuberculosis, hepatitis B or C and people with high cardiovascular risk; and cases with CD4+ T lymphocytes less than 350 cells/mm3 and those symptomatic, due to the critical impact on morbimortality.22