BIK and cancer: The hallmark processes of cancer we identified as relevant to TNBC via our relatively unbiased nomination and testing for predictive linkage between gene expression and survival include genes such as BIK, encoding a protein that balances proapoptotic and antiapoptotic signaling roles, and key sphingolipid metabolism enzymes that can catalyze interconversion of a lipid class that functions with anticancer propensity into lipid species that promote cancer, each having effects on cellular motility, differentiation, apoptosis, inflammation/immunity, and angiogenesis.