More interestingly, an article by Littera et al., examined 182 Sardinian subjects affected by SARS-CoV-2 infection, unravelling an increased risk for severe illness conferred by G6PD deficiency due to the G6PD Med mutation compared to the paucisymptomatic presentation associated to G6PD-negative status (25.6% vs 9.8%, OR 3.2; 95% CI 1.3-7.9, P = 0.015) [185]. The gene discussed is G6PD; the disease is G6PD deficiency.