Recently, Feng et al. reported that lncRNA PCNAP1 is associated with HBV-infectious HCC patients and acts as a competitive endogenous RNA (ceRNA) to sponge miR-154, therefore regulating the expression of PCNA, which interacts with HBV cccDNA, finally, enhancing HCC growth. The gene discussed is PCNA; the disease is hepatocellular carcinoma.