Besides, when comparing the prediction performance between this XGBoost-based model and risk systems constructed on the basis of FOXP3 and TIL PD-L1, TIL PD-1, TIL LAG-3, CD3, CD4, CD8, or PD-L1 on tumor cells, we found this XGBoost-based model exhibited the best prediction performance with the maximal AUC value. This evidence concerns the gene CD274 and neoplasm.