Very recently, a series of lncRNAs have been reported as cancer biomarkers, such as TP73-AS1 in glioma[19], BGL3 in papillary thyroid carcinoma[20], WT1-AS in lung adenocarcinoma[21], PHACTR2-AS1 in tongue squamous cell carcinoma[22], CRNDE in osteosarcoma[23] and LINC01451 in bladder cancer[24]. This evidence concerns the gene PHACTR2 and osteosarcoma.