SOX4 and osteoporosis: When the CC genotype of SOX4 gene rs201335371 as a reference, the CT genotype, TT genotype, dominant model, recessive model, and additive model were associated with a reduced risk of osteoporosis (P < 0.05) and the risk of osteoporosis in the T allele carriers was 0.54 times that in the C allele carriers (95% CI 0.43–0.69, P < 0.01).