TLR4 and Parkinson disease: Rab10 is associated with ciliogenesis and TLR4 recycling from endo-somes/Golgi to the plasma membrane (Banton et al., 2014; Homma and Fukuda, 2016; Peranen et al., 1996; Rivero-Rios et al., 2019) and dysregulation of these highly vital cellular activities could provide a mechanism leading to differential neuronal vulnerability, dopaminergic cell death, and hence PD.