In cancer, cysteinylation of antigens can confer evasion from T cell recognition, but processing by the interferon (IFN)-γ-inducible lysosomal thiol reductase (GILT) can remove antigen cysteinylation and induce antigen processing and T cell responses in the context of melanoma (Norton and Haque, 2009). Here, IFI30 is linked to melanoma.