Dr. Kanmin Xue discussed clinical studies using subretinal injections of an AAV2 vector expressing REP1 to treat choroideremia and of an AAV8 vector expressing codon-optimized retinitis pigmentosa GTPase regulator gene (RPGR) to treat X-linked retinitis pigmentosa (Table 1B). The gene discussed is CHM; the disease is choroideremia.