To understand the specific effects of wt and mutant KRAS on the expression and functions of AATs, we used a human CRC cell line with mutant KRAS (HCT116‐KRASWT/G13D) and its isogenic cell line (HKe3 parental‐KRASWT/G13D−), the independent HCT116 clone in which the endogenous mutant KRASG13D allele was deleted through targeted homologous recombination [36]. Here, KRAS is linked to colorectal carcinoma.