AKT1 and non-small cell lung carcinoma: Forkhead box protein C2 (FOXC2) was shown to promote resistance to the same drug by induction of EMT in non-small cell lung cancer A549 cells by activating v-akt murine thymoma viral oncogene homolog 1/ Glycogen synthase kinase 3 (AKT/GSK3) signaling pathway and increased expression of Snail (He et al. 2018).