Another study reports that, Circ_0008274 is up-regulated in HCC tissues and correlated with poor prognosis in patients with HCC; circ_0008274 silencing suppressed tumor growth in vivo and blocked proliferation, colony formation, cell cycle progression, migration, and invasion of HCC cells in vitro via miR-526b-5p/RAB1A axis [19]. The gene discussed is RAB1A; the disease is neoplasm.