Our splicing regulation network analysis showed some splicing factors might be correlated with prognosis-related AS events, including SPEN, SF3B5, RNPC3, LUC7L3, SRSF11 and PRPF38B (Fig. 6), suggesting that these splicing factors could play crucial roles in ovarian cancer development. Here, PRPF38B is linked to ovarian carcinoma.