KCND2 and epilepsy: miR-324-5p has also been investigated in relation to epilepsy; in a murine model of epilepsy, whereby wild-type (WT) mice were injected with pilocarpine in order to evoke seizure activity, the use of a miR-324-5p antagomir was found to reduce the incidence of epileptic events30, purportedly by downregulating the expression of Kcnd2, a gene encoding the potassium channel protein Kv4.229,30.