Two epilepsy-associated genes are identified to be DE in the hippocampus and neocortex in mice lacking Mir324; Suox and Pnpo. Additionally, Suox is shown to be a direct target of miR-324-5p in vitro, as is Cd300lf, a gene indirectly associated with neurological function through MMPs. The gene discussed is PNPO; the disease is epilepsy.