CNR2 and frontotemporal dementia: In relation to this personalized medicine, it is also interesting to highlight the implication that modulation of the CB2 receptor would have in the development of disease-modifying drugs for frontotemporal dementia (FTD) spectrum disorders, although to date no change in CB2 levels (neither in microglia nor in neurons) has been described in this pathology, so it would be interesting to determine the status of CB2 and its cellular location.