IL13RA2 and glioblastoma: In glioblastoma, IL13RA2 has been shown to cooperate with mutant EGFRvIII to mediate growth [43], while EGFR mutations including EGFRvIII are believed to not be widely recurrent in DIPG[25, 53]which may limit the importance of IL13RA2 in DIPG progression.