Methyltransferase complex components (METTL3, METTL14, WTAP), demethylases (FTO, ALKBH5), and the common m6A binding protein YTHDF2 are all highly expressed in patients with various subtypes of AML [67, 69–72, 76–78]. The gene discussed is METTL3; the disease is acute myeloid leukemia.