For the NOS3, rs1799983 SNP, the prevalences of hypertension among women with GG, GT and TT genotypes were 24.5%, 23.0% and 52.0%, respectively, with a statistically significant difference between TT and GG (PR = 1.54; 95% CI 1.27–1.86; p < 0.001). This evidence concerns the gene NOS3 and hypertensive disorder.