As serum ADA levels quartiles increased, age, ratio of female to male, diabetes duration, ratio of hypertension, SBP, ALT and AST significantly increased (all p values for trend < 0.05), while BMI, DBP, TG, TC, HDLC and LDLC showed no differences (all p values for trend > 0.05). The gene discussed is ADA; the disease is Hypertension.