Various inflammatory and nutritional markers, such as C-reactive protein-to-albumin ratio (CRP/ALB ratio), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), prognostic nutritional index (PNI), have been confirmed as prognostic indicators of esophageal cancer [16–20]. This evidence concerns the gene CRP and esophageal cancer.