Several microRNAs have been described to negatively regulate TNFAIP1 in a large number of tumors, confirming its pivotal role of tumor suppressor: miR-372 and miR-373 in gastric carcinoma [42–45], miR-224 and miR-424 in non-small cell lung cancer (NSCLC) [46, 47], miR-181a in pancreatic cancer [48]. Here, TNFAIP1 is linked to non-small cell lung carcinoma.