HAMP and hepatocellular carcinoma: Our results showed that 2212 of 3507 hepatocytes in the normal liver dataset and 10 of 320 hepatocytes in the HCC dataset expressed HAMP. Furthermore, with the S1 index > 0.1 as a threshold for proliferative cells, we found that 14.5% of proliferative cells in the normal liver dataset and 1.7% of proliferative cells in the HCC dataset expressed HAMP. The significant differences in HAMP-expressing cells between the two datasets reflect the on/off state of HAMP expression in normal liver and HCC tissue.