ERBB2 and breast cancer: As shown in Table 2, univariate COX analysis exhibited that worse OS was associated with pathological stage III-IV than I-II (HR = 2.28, 95% CI: 1.45–3.61), lymph node involvement than non-involvement (HR = 2.04, 95% CI: 1.26–3.30), distant metastasis positive than negative (HR = 4.35, 95% CI: 2.16–8.75), PR positive than negative (HR = 2.88, 95% CI: 1.17–7.12), HER-2 positive BC than HR positive BC (HR = 2.68, 95% CI: 1.07–6.76), infiltrating ductal BC than infiltrating lobular BC (HR = 0.29, 95% CI: 0.12–0.66), and low than high FST expression (HR = 0.47, 95% CI: 0.27–0.82).