PRRX1 and chronic myelogenous leukemia, BCR-ABL1 positive: To date, only five cases of NUP98-PMX1 fusion have been reported, involving chronic myeloid leukemia in the accelerated phase, blast crisis, or therapy-related acute myeloid leukemia (AML) (Table 1) [5–8]; no case of de novo AML carrying the NUP98-PMX1 fusion gene has been reported.